comparative proteomics HELP
ProteoSign is an online service for protein differential expression (or abundance) analysis designed with the end-proteomics user in mind.
Borrowing from the experience of the microarray field, ProteoSign software utilizes the well-established Linear Models For Microarray Data (LIMMA) methodology for assessing statistical significance in protein abundance differences between two or more proteome states.
ProteoSign aims to fully automate the process of statistically evaluating differential expression in mass spectrometry-based bottom-up (shotgun) quantitative proteomics data by requiring minimal user interaction time and generating publication-quality data plots.
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