comparative proteomics HELP
ProteoSign is an online service for protein differential expression (or abundance) analysis designed with the end-proteomics user in mind.
Borrowing from the experience of the microarray field, ProteoSign software utilizes the well-established Linear Models For Microarray Data (LIMMA) methodology for assessing statistical significance in protein abundance differences between two or more proteome states.
ProteoSign aims to fully automate the process of statistically evaluating differential expression in mass spectrometry-based bottom-up (shotgun) quantitative proteomics data by requiring minimal user interaction time and generating publication-quality data plots.
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ProteoSign supports data sets that have biological or technical replicates represented as different tags. Please choose the options below that best describe your experiment and click Next:
If you have no technical replicates select "Raw Files" as the corresponding option
My biological replicates are represented as different Raw Files Tags
My technical replicates are represented as different Raw Files Tags
My conditions are represented as different Raw Files Tags